60 years Of Providing Digestive Symptom Relief | Iberogast®

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History

Date 1960s surrounded by leaves and old-fashioned bottle of Iberogast with its packaging next to it.

1960 – Iberogast® was launched in Germany

The original Iberogast® was developed in the late 1950s and went into production in 1960. At first, this was an extremely laborious process, as everything – including the extraction, mixing, bottling and packaging – was carried out by hand. Scientific research on the product intensified over the course of the 1960s.

Date 1970s surrounded by leaves, bottle of Iberogast with yellow label and its matching packaging next to it.

The 1970s – production was optimised and clinical research initiated

In the 1960s, Iberogast® was launched as a pharmacy-only product, but already by the 1970s, it became obvious that decisive steps needed to be taken to expand and optimise production processes. As the decade was drawing to a close, the first clinical trials were conducted to demonstrate the product’s efficacy and tolerability, and the results were published.

Date 1980s surrounded by leaves, grayish bottle of Iberogast with its matching packaging next to it.

The 1980s and the 1990s – the dual-action principle

In the early 1980s, the collaboration with the most renowned pharmacologist of the time, Professor Ammon of the University of Tübingen, was initiated. In 1986, this intense preclinical research cooperation led to the discovery of a key feature of Iberogast®: its dual mode action. The different effects of the medicine on the gastrointestinal tract – relaxation on the one hand and stimulation on the other – prompted a spate of further research activities and publications.19 From the mid-1980s, extensive research was carried out on Iberogast® to further demonstrate also its safety. Additionally, Iberogast® started to be marketed internationally for the first time in the 1980s. By the late 1990s, the results of all safety and efficacy studies had been published. The design of all studies followed the latest scientific guidelines and met the current requirements for newly approved medications after the international guidelines of the ICH (International Conference on Harmonization for GCP — Good Clinical Practice). All of these early studies demonstrated that Iberogast® is well tolerated and effective in relieving gastrointestinal symptoms of Functional Dyspepsia and Irritable Bowel Syndrome.10

Date 2000s surrounded by leaves, white and green bottle of Iberogast with its matching packaging next to it.

The early 2000s – positive effect on IBS shown

At the dawn of the new millennium, researchers described the significance of Iberis amara, as well as the mutually reinforcing effects of the individual medicinal plant extracts. The year 2003 proved to be especially crucial due to the discovery of the specific effects of Iberogast® on various parts of the stomach: the relaxing impact on the upper part of the stomach that stores food and the stimulating impact on the lower part of the stomach that transports food.20 Understandably, the findings stirred up considerable interest within the medical community. In 2007, a clinical trial confirmed this region-specificity of Iberogast® on different parts of the stomach in humans. In 2004, researchers described the product’s favourable mode of action in Irritable Bowel Syndrome and Functional Dyspepsia. In 2006, the multiple effects of Iberogast® were finally summarised as the multi-target principle and this description is valid ever since. Numerous investigations on further modes of action followed substantiating the multi-target principle.

Date 2010s surrounded by leaves, modern white and green bottle of Iberogast with its matching packaging next to it.

The 2010s – Iberogast® in the fast lane

Results from the latest non-interventional study in 2013 confirmed the rapid onset of action of Iberogast® that starts working within a few minutes after intake. No other herbal remedy has been so well researched, and its mechanism of action is still the subject of studies carried out by numerous pharmacological experts.

Date 2013s surrounded by leaves, current white and green bottle of Iberogast with its matching packaging next to it.

2013 – Bayer acquired Steigerwald

In 2013, Bayer acquired Steigerwald Arzneimittelwerk. Iberogast® became part of Bayer’s brand portfolio and started benefiting from the company’s global expertise in pharmaceuticals. Bayer uses the same rigorous manufacturing and quality standards that are applied to all of its medicines and helps to make this fast-acting, effective, state-of-the-art product available to many more people around the world.10

Date 2020s surrounded by leaves, current white and green bottle of Iberogast with its matching packaging next to it.

2020

The year 2020 marks Iberogast’s 60 year anniversary. To this day, the product remains highly recommended by doctors as a fast, effective, well-tolerated liquid for people struggling with functional digestive symptoms.10

A bottle of Iberogast standing on moss, with packaging next to it, surrounded by forest.

Iberogast®

Disturbances in the gastrointestinal tract are usually not only extremely unpleasant and associated with numerous complaints, they often make a normal everyday life even harder. It’s good that there is Iberogast®: The combination of nine medicinal plants targets both the underlying causes and the annoying symptoms.3

A bottle of Iberogast on green background, surrounded by herbs

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